Neoadjuvant Therapy
Neoadjuvant therapy is an adjunctive threapy given before primary therapy and it has become an integral part of modern multidisciplinary cancer management. The outcome of the neoadjuvant therapy is summarized for common malignant solid tumors, based on large, randomized, controlled trials. Neoadjuvant therapy enables organ preservation is cases of locally advanced rectal, laryngeal, and breast cancer. But it can not improve the overall survival when compared with definitive treatment followed by adjuvant therapy. Patients who go for neoadjuvant therapy before radical surgery, in case of locally advanced bladder and cervical cancer appear to have a better survival than those only receiving definitive therapies. However it is still not clear whether neoadjuvant approach is superior than definitive therapy followed by adjuvant therapy.
The main aim of the neoadjuvant therapy is to reduce the size or extent of the cancer before using radical treatment intervention. So as to make the procedures easier and increasing the propability to succeed. Hence reducing the consequences of a more extensive treatment technique that would have required if the size and the extent of the tumor was not reduced. One example of this therapy : prior to radical radiotherapy, neoadjuvant hormone therapy is given for adenocarcinoma of the prostate.
Neoadjuvant chemotherapy is often given to woman in case of breast cancer for shrinking the tumor that is inoperable in its original state, so that it can be removed surgically. In case of woman whose tumor can be removed by mastectomy may receive neoadjuvant therapy to shrink the tumor enough so as to allow breast-conserving surgery.
The systemic therapies such as chemotherapy, immunotherapy or hormone therapy or radiation therapy are mostly used in case where cancers are locally advanced and at later stage an operation is technically planned. The purpose of this therapy is to effectively reduce the difficulty and morbidity accociated with the extensive procedure. To shrink the volume of the tumor so as to turn it from untreatable to treatable form is the main purpose of this therapy. Many times it is difficult to find which surrounding structures are directly involved in the disease and which are just showing signs of inflamation. By the help of the administering therapy a distinction can be made. Doctors recommend this therapy in a hope that a possitive response will be seen on the basis of which they can decide what will be the best course of action. But everyone is not suitable for this therapy as because it can be extremely toxic. In some cases, reactions are very severe and further treatments like surgery can not be done as because the patient becomes to unfit for anesthesia.
Common tumors that use this concept:
Breast Cancer
Colorectal cancer
Lung cancer
Esophageal cancer
Neoadjuvant therapy or inductive therapy can improve the result of the treatment substantially, although this therapy does not contribute much to the outcome of the treatment. Like for example neoadjuvant therapy enables pateints having large breast cancer to go for breast canserving surgery. Patients with locally advanced laryngeal cancer can have their vocal function preserved by the help of this therapy. After undergoing this therapy many patients with rectal cancer can avoid permanent colostomy. In case of certain type of cancers, neoadjuvant therapy can improve the survival in long run. There is an increase in the popularity of this treatment in the recent year. The number of clinical trials on this topic has been published from 2000 to 2003 which exceed the number published during the entire previous decade.
India has gained repute across the world for its highly qualified and experienced medical teams, which are competent enough to provide highly specialized care to medical tourists from across the world. Leading cancer hospitals in India are facilated with latest drugs with clinical research back up for such surgical treatment. World Class cancer treatment is offered at cancer hospitals in India, comparable with any of the western countries. India has state-of-the-art Hospitals and the well qualified doctors. With the best infrastructure, the best possible Medical facilities, accompanied with the most competitive pricing, you can get the treatment done in India at the lowest charges.
The list of India Best Hospitals include Apollo, Fortis, Max Healthcare, Escorts, AIIMs, Wockhardt, etc. A few top Medical tourism providers are India4health, Asiahealth and Indiaheals.
Neoadjuvant therapy is an adjunctive threapy given before primary therapy and it has become an integral part of modern multidisciplinary cancer management. The outcome of the neoadjuvant therapy is summarized for common malignant solid tumors, based on large, randomized, controlled trials. Neoadjuvant therapy enables organ preservation is cases of locally advanced rectal, laryngeal, and breast cancer. But it can not improve the overall survival when compared with definitive treatment followed by adjuvant therapy. Patients who go for neoadjuvant therapy before radical surgery, in case of locally advanced bladder and cervical cancer appear to have a better survival than those only receiving definitive therapies. However it is still not clear whether neoadjuvant approach is superior than definitive therapy followed by adjuvant therapy.
The main aim of the neoadjuvant therapy is to reduce the size or extent of the cancer before using radical treatment intervention. So as to make the procedures easier and increasing the propability to succeed. Hence reducing the consequences of a more extensive treatment technique that would have required if the size and the extent of the tumor was not reduced. One example of this therapy : prior to radical radiotherapy, neoadjuvant hormone therapy is given for adenocarcinoma of the prostate.
Neoadjuvant chemotherapy is often given to woman in case of breast cancer for shrinking the tumor that is inoperable in its original state, so that it can be removed surgically. In case of woman whose tumor can be removed by mastectomy may receive neoadjuvant therapy to shrink the tumor enough so as to allow breast-conserving surgery.
The systemic therapies such as chemotherapy, immunotherapy or hormone therapy or radiation therapy are mostly used in case where cancers are locally advanced and at later stage an operation is technically planned. The purpose of this therapy is to effectively reduce the difficulty and morbidity accociated with the extensive procedure. To shrink the volume of the tumor so as to turn it from untreatable to treatable form is the main purpose of this therapy. Many times it is difficult to find which surrounding structures are directly involved in the disease and which are just showing signs of inflamation. By the help of the administering therapy a distinction can be made. Doctors recommend this therapy in a hope that a possitive response will be seen on the basis of which they can decide what will be the best course of action. But everyone is not suitable for this therapy as because it can be extremely toxic. In some cases, reactions are very severe and further treatments like surgery can not be done as because the patient becomes to unfit for anesthesia.
Common tumors that use this concept:
Breast Cancer
Colorectal cancer
Lung cancer
Esophageal cancer
Neoadjuvant therapy or inductive therapy can improve the result of the treatment substantially, although this therapy does not contribute much to the outcome of the treatment. Like for example neoadjuvant therapy enables pateints having large breast cancer to go for breast canserving surgery. Patients with locally advanced laryngeal cancer can have their vocal function preserved by the help of this therapy. After undergoing this therapy many patients with rectal cancer can avoid permanent colostomy. In case of certain type of cancers, neoadjuvant therapy can improve the survival in long run. There is an increase in the popularity of this treatment in the recent year. The number of clinical trials on this topic has been published from 2000 to 2003 which exceed the number published during the entire previous decade.
India has gained repute across the world for its highly qualified and experienced medical teams, which are competent enough to provide highly specialized care to medical tourists from across the world. Leading cancer hospitals in India are facilated with latest drugs with clinical research back up for such surgical treatment. World Class cancer treatment is offered at cancer hospitals in India, comparable with any of the western countries. India has state-of-the-art Hospitals and the well qualified doctors. With the best infrastructure, the best possible Medical facilities, accompanied with the most competitive pricing, you can get the treatment done in India at the lowest charges.
The list of India Best Hospitals include Apollo, Fortis, Max Healthcare, Escorts, AIIMs, Wockhardt, etc. A few top Medical tourism providers are India4health, Asiahealth and Indiaheals.
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